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3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling

BACKGROUND: Saussurea involucrata (Kar. et Kir.) (S. involucrate), is a rare traditional Chinese medicinal herb. Rutin and hispidulin as well as their metabolites are flavonoids of the flavonol type that abound in S. involucrata, which has been reported to inhibit nonoxidative advanced glycation end...

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Detalles Bibliográficos
Autores principales: Su, Kang-Yi, Yu, Chao Yuan, Chen, Ya-Ping, Hua, Kuo-Feng, Chen, Yi-Lin Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900474/
https://www.ncbi.nlm.nih.gov/pubmed/24417898
http://dx.doi.org/10.1186/1472-6882-14-21