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Recombinant Production of the Amino Terminal Cytoplasmic Region of Dengue Virus Non-Structural Protein 4A for Structural Studies

BACKGROUND: Dengue virus (DENV) is a mosquito-transmitted positive single strand RNA virus belonging to the Flaviviridae family. DENV causes dengue fever, currently the world's fastest-spreading tropical disease. Severe forms of the disease like dengue hemorrhagic fever and dengue shock syndrom...

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Detalles Bibliográficos
Autores principales: Hung, Yu-Fu, Valdau, Olga, Schünke, Sven, Stern, Omer, Koenig, Bernd W., Willbold, Dieter, Hoffmann, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900556/
https://www.ncbi.nlm.nih.gov/pubmed/24466115
http://dx.doi.org/10.1371/journal.pone.0086482