Induction of a Stringent Metabolic Response in Intracellular Stages of Leishmania mexicana Leads to Increased Dependence on Mitochondrial Metabolism

Leishmania parasites alternate between extracellular promastigote stages in the insect vector and an obligate intracellular amastigote stage that proliferates within the phagolysosomal compartment of macrophages in the mammalian host. Most enzymes involved in Leishmania central carbon metabolism are...

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Detalles Bibliográficos
Autores principales: Saunders, Eleanor C., Ng, William W., Kloehn, Joachim, Chambers, Jennifer M., Ng, Milica, McConville, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900632/
https://www.ncbi.nlm.nih.gov/pubmed/24465208
http://dx.doi.org/10.1371/journal.ppat.1003888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900632/
https://www.ncbi.nlm.nih.gov/pubmed/24465208
http://dx.doi.org/10.1371/journal.ppat.1003888

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