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Variation in RNA Virus Mutation Rates across Host Cells

It is well established that RNA viruses exhibit higher rates of spontaneous mutation than DNA viruses and microorganisms. However, their mutation rates vary amply, from 10(−6) to 10(−4) substitutions per nucleotide per round of copying (s/n/r) and the causes of this variability remain poorly underst...

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Detalles Bibliográficos
Autores principales: Combe, Marine, Sanjuán, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900646/
https://www.ncbi.nlm.nih.gov/pubmed/24465205
http://dx.doi.org/10.1371/journal.ppat.1003855