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Variation in RNA Virus Mutation Rates across Host Cells
It is well established that RNA viruses exhibit higher rates of spontaneous mutation than DNA viruses and microorganisms. However, their mutation rates vary amply, from 10(−6) to 10(−4) substitutions per nucleotide per round of copying (s/n/r) and the causes of this variability remain poorly underst...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900646/ https://www.ncbi.nlm.nih.gov/pubmed/24465205 http://dx.doi.org/10.1371/journal.ppat.1003855 |