Chloroquine Is Grossly Under Dosed in Young Children with Malaria: Implications for Drug Resistance

BACKGROUND: Plasmodium falciparum malaria is treated with 25 mg/kg of chloroquine (CQ) irrespective of age. Theoretically, CQ should be dosed according to body surface area (BSA). The effect of dosing CQ according to BSA has not been determined but doubling the dose per kg doubled the efficacy of CQ...

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Detalles Bibliográficos
Autores principales: Ursing, Johan, Eksborg, Staffan, Rombo, Lars, Bergqvist, Yngve, Blessborn, Daniel, Rodrigues, Amabelia, Kofoed, Poul-Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900653/
https://www.ncbi.nlm.nih.gov/pubmed/24466245
http://dx.doi.org/10.1371/journal.pone.0086801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900653/
https://www.ncbi.nlm.nih.gov/pubmed/24466245
http://dx.doi.org/10.1371/journal.pone.0086801

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