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Chloroquine Is Grossly Under Dosed in Young Children with Malaria: Implications for Drug Resistance
BACKGROUND: Plasmodium falciparum malaria is treated with 25 mg/kg of chloroquine (CQ) irrespective of age. Theoretically, CQ should be dosed according to body surface area (BSA). The effect of dosing CQ according to BSA has not been determined but doubling the dose per kg doubled the efficacy of CQ...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900653/ https://www.ncbi.nlm.nih.gov/pubmed/24466245 http://dx.doi.org/10.1371/journal.pone.0086801 |