Soluble HIV-1 Envelope Immunogens Derived from an Elite Neutralizer Elicit Cross-Reactive V1V2 Antibodies and Low Potency Neutralizing Antibodies

We evaluated four gp140 Envelope protein vaccine immunogens that were derived from an elite neutralizer, subject VC10042, whose plasma was able to potently neutralize a wide array of genetically distinct HIV-1 isolates. We sought to determine whether soluble Envelope proteins derived from the viruse...

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Detalles Bibliográficos
Autores principales: Carbonetti, Sara, Oliver, Brian G., Glenn, Jolene, Stamatatos, Leonidas, Sather, D. Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900663/
https://www.ncbi.nlm.nih.gov/pubmed/24466285
http://dx.doi.org/10.1371/journal.pone.0086905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900663/
https://www.ncbi.nlm.nih.gov/pubmed/24466285
http://dx.doi.org/10.1371/journal.pone.0086905

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