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Mechanisms of the Scaffold Subunit in Facilitating Protein Phosphatase 2A Methylation

The function of the biologically essential protein phosphatase 2A (PP2A) relies on formation of diverse heterotrimeric holoenzymes, which involves stable association between PP2A scaffold (A) and catalytic (C or PP2Ac) subunits and binding of variable regulatory subunits. Holoenzyme assembly is high...

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Detalles Bibliográficos
Autores principales: Stanevich, Vitali, Zheng, Aiping, Guo, Feng, Jiang, Li, Wlodarchak, Nathan, Xing, Yongna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900686/
https://www.ncbi.nlm.nih.gov/pubmed/24466300
http://dx.doi.org/10.1371/journal.pone.0086955