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Expression and Purification of Chaperone-Active Recombinant Clusterin

Clusterin was the first described secreted mammalian chaperone and is implicated as being a key player in both intra- and extracellular proteostasis. Its unique combination of structural features and biological chaperone activity has, however, previously made it very challenging to express and purif...

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Detalles Bibliográficos
Autores principales: Dabbs, Rebecca A., Wilson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900688/
https://www.ncbi.nlm.nih.gov/pubmed/24466307
http://dx.doi.org/10.1371/journal.pone.0086989