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Expression and Purification of Chaperone-Active Recombinant Clusterin
Clusterin was the first described secreted mammalian chaperone and is implicated as being a key player in both intra- and extracellular proteostasis. Its unique combination of structural features and biological chaperone activity has, however, previously made it very challenging to express and purif...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900688/ https://www.ncbi.nlm.nih.gov/pubmed/24466307 http://dx.doi.org/10.1371/journal.pone.0086989 |