An Asp7Gly Substitution in PPARG Is Associated with Decreased Transcriptional Activation Activity

As the master regulator of adipogenesis, peroxisome proliferator-activated receptor gamma (PPARG) is required for the accumulation of adipose tissue and hence contributes to obesity. A previous study showed that the substitution of +20A>G in PPARG changed the 7(th) amino acid from Asp to Gly, cre...

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Detalles Bibliográficos
Autores principales: Hua, Liushuai, Wang, Jing, Li, Mingxun, Sun, Xiaomei, Zhang, Liangzhi, Lei, Chuzhao, Lan, Xianyong, Fang, Xingtang, Zhao, Xin, Chen, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900691/
https://www.ncbi.nlm.nih.gov/pubmed/24466299
http://dx.doi.org/10.1371/journal.pone.0086954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900691/
https://www.ncbi.nlm.nih.gov/pubmed/24466299
http://dx.doi.org/10.1371/journal.pone.0086954

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