Regulation of MYC Expression and Differential JQ1 Sensitivity in Cancer Cells

High level MYC expression is associated with almost all human cancers. JQ1, a chemical compound that inhibits MYC expression is therapeutically effective in preclinical animal models in midline carcinoma, and Burkitt’s lymphoma (BL). Here we show that JQ1 does not inhibit MYC expression to a similar...

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Detalles Bibliográficos
Autores principales: Fowler, Trent, Ghatak, Payel, Price, David H., Conaway, Ronald, Conaway, Joan, Chiang, Cheng-Ming, Bradner, James E., Shilatifard, Ali, Roy, Ananda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900694/
https://www.ncbi.nlm.nih.gov/pubmed/24466310
http://dx.doi.org/10.1371/journal.pone.0087003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900694/
https://www.ncbi.nlm.nih.gov/pubmed/24466310
http://dx.doi.org/10.1371/journal.pone.0087003

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