Novel Analogue of Colchicine Induces Selective Pro-Death Autophagy and Necrosis in Human Cancer Cells

Colchicine, a natural product of Colchicum autumnae currently used for gout treatment, is a tubulin targeting compound which inhibits microtubule formation by targeting fast dividing cells. This tubulin-targeting property has lead researchers to investigate the potential of colchicine and analogs as...

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Detalles Bibliográficos
Autores principales: Larocque, Kristen, Ovadje, Pamela, Djurdjevic, Sinisa, Mehdi, Mariam, Green, James, Pandey, Siyaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900699/
https://www.ncbi.nlm.nih.gov/pubmed/24466327
http://dx.doi.org/10.1371/journal.pone.0087064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900699/
https://www.ncbi.nlm.nih.gov/pubmed/24466327
http://dx.doi.org/10.1371/journal.pone.0087064

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