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The Antidepressant 5-HT(2A) Receptor Antagonists Pizotifen and Cyproheptadine Inhibit Serotonin-Enhanced Platelet Function
There is considerable interest in defining new agents or targets for antithrombotic purposes. The 5-HT(2A) receptor is a G-protein coupled receptor (GPCR) expressed on many cell types, and a known therapeutic target for many disease states. This serotonin receptor is also known to regulate platelet...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900701/ https://www.ncbi.nlm.nih.gov/pubmed/24466319 http://dx.doi.org/10.1371/journal.pone.0087026 |