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Activation of Duck RIG-I by TRIM25 Is Independent of Anchored Ubiquitin

Retinoic acid inducible gene I (RIG-I) is a viral RNA sensor crucial in defense against several viruses including measles, influenza A and hepatitis C. RIG-I activates type-I interferon signalling through the adaptor for mitochondrial antiviral signaling (MAVS). The E3 ubiquitin ligase, tripartite m...

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Detalles Bibliográficos
Autores principales: Miranzo-Navarro, Domingo, Magor, Katharine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900705/
https://www.ncbi.nlm.nih.gov/pubmed/24466302
http://dx.doi.org/10.1371/journal.pone.0086968