Human Liver Cell Trafficking Mutants: Characterization and Whole Exome Sequencing

The HuH7 liver cell mutant Trf1 is defective in membrane trafficking and is complemented by the casein kinase 2α subunit CK2α’’. Here we identify characteristic morphologies, trafficking and mutational changes in six additional HuH7 mutants Trf2-Trf7. Trf1 cells were previously shown to be severely...

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Detalles Bibliográficos
Autores principales: Yuan, Fei, Snapp, Erik L., Novikoff, Phyllis M., Suadicani, Sylvia O., Spray, David C., Potvin, Barry, Wolkoff, Allan W., Stanley, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900707/
https://www.ncbi.nlm.nih.gov/pubmed/24466322
http://dx.doi.org/10.1371/journal.pone.0087043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900707/
https://www.ncbi.nlm.nih.gov/pubmed/24466322
http://dx.doi.org/10.1371/journal.pone.0087043

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