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Human Liver Cell Trafficking Mutants: Characterization and Whole Exome Sequencing
The HuH7 liver cell mutant Trf1 is defective in membrane trafficking and is complemented by the casein kinase 2α subunit CK2α’’. Here we identify characteristic morphologies, trafficking and mutational changes in six additional HuH7 mutants Trf2-Trf7. Trf1 cells were previously shown to be severely...
Autores principales: | Yuan, Fei, Snapp, Erik L., Novikoff, Phyllis M., Suadicani, Sylvia O., Spray, David C., Potvin, Barry, Wolkoff, Allan W., Stanley, Pamela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900707/ https://www.ncbi.nlm.nih.gov/pubmed/24466322 http://dx.doi.org/10.1371/journal.pone.0087043 |
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