The RhoGAP Activity of Myosin IXB Is Critical for Osteoclast Podosome Patterning, Motility, and Resorptive Capacity

Osteoclasts are large, multinucleated cells of the monocyte-macrophage lineage that generate specialized substrate adhesion complexes to facilitate their function as bone-degrading cells. The patterning and function of these actin-based complexes, podosomes and sealing zones, are regulated by the sm...

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Detalles Bibliográficos
Autores principales: McMichael, Brooke K., Scherer, Katharine F., Franklin, Nicole C., Lee, Beth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900720/
https://www.ncbi.nlm.nih.gov/pubmed/24466350
http://dx.doi.org/10.1371/journal.pone.0087402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900720/
https://www.ncbi.nlm.nih.gov/pubmed/24466350
http://dx.doi.org/10.1371/journal.pone.0087402

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