Ketoconazole Inhibits the Cellular Uptake of Anandamide via Inhibition of FAAH at Pharmacologically Relevant Concentrations

BACKGROUND: The antifungal compound ketoconazole has, in addition to its ability to interfere with fungal ergosterol synthesis, effects upon other enzymes including human CYP3A4, CYP17, lipoxygenase and thromboxane synthetase. In the present study, we have investigated whether ketoconazole affects t...

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Detalles Bibliográficos
Autores principales: Björklund, Emmelie, Larsson, Therése N. L., Jacobsson, Stig O. P., Fowler, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900727/
https://www.ncbi.nlm.nih.gov/pubmed/24466356
http://dx.doi.org/10.1371/journal.pone.0087542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900727/
https://www.ncbi.nlm.nih.gov/pubmed/24466356
http://dx.doi.org/10.1371/journal.pone.0087542

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