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Epigenetic changes during hematopoietic cell granulocytic differentiation – comparative analysis of primary CD34+ cells, KG1 myeloid cells and mature neutrophils

BACKGROUND: Epigenetic regulation is known to affect gene expression, and recent research shows that aberrant DNA methylation patterning and histone modifications may play a role in leukemogenesis. In order to highlight the co-operation of epigenetic mechanisms acting during the latter process it is...

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Detalles Bibliográficos
Autores principales: Navakauskienė, Rūta, Borutinskaitė, Veronika V, Treigytė, Gražina, Savickienė, Jūratė, Matuzevičius, Dalius, Navakauskas, Dalius, Magnusson, Karl-Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900736/
https://www.ncbi.nlm.nih.gov/pubmed/24443786
http://dx.doi.org/10.1186/1471-2121-15-4