Differential effects on KCC2 expression and spasticity of ALS and traumatic injuries to motoneurons

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease manifested by progressive muscle atrophy and paralysis due to the loss of upper and lower motoneurons (MN). Spasticity appears in ALS patients leading to further disabling consequences. Loss of the inhibitory tone induced by downregu...

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Detalles Bibliográficos
Autores principales: Mòdol, Laura, Mancuso, Renzo, Alé, Albert, Francos-Quijorna, Isaac, Navarro, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900854/
https://www.ncbi.nlm.nih.gov/pubmed/24478630
http://dx.doi.org/10.3389/fncel.2014.00007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900854/
https://www.ncbi.nlm.nih.gov/pubmed/24478630
http://dx.doi.org/10.3389/fncel.2014.00007

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