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Epigenetic silencing of ARRDC3 expression in basal-like breast cancer cells

Arrestin domain-containing 3 (ARRDC3) is a tumor suppressor whose expression is either lost or suppressed in basal-like breast cancer (BLBC). However, the mechanism by which BLBC suppresses ARRDC3 expression is not established. Here, we show that expression of ARRDC3 in BLBC cells is suppressed at t...

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Detalles Bibliográficos
Autores principales: Soung, Young Hwa, Pruitt, Kevin, Chung, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900932/
https://www.ncbi.nlm.nih.gov/pubmed/24457910
http://dx.doi.org/10.1038/srep03846