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Modular adeno-associated virus (rAAV) vectors used for cellular virus-directed enzyme prodrug therapy

The pre-clinical and clinical development of viral vehicles for gene transfer increased in recent years, and a recombinant adeno-associated virus (rAAV) drug took center stage upon approval in the European Union. However, lack of standardization, inefficient purification methods and complicated reta...

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Detalles Bibliográficos
Autores principales: Hagen, Sven, Baumann, Tobias, Wagner, Hanna J., Morath, Volker, Kaufmann, Beate, Fischer, Adrian, Bergmann, Stefan, Schindler, Patrick, Arndt, Katja M., Müller, Kristian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901000/
https://www.ncbi.nlm.nih.gov/pubmed/24457557
http://dx.doi.org/10.1038/srep03759