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Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity

Stress in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), a signaling mechanism that allows cellular adaptation to ER stress by engaging pro-adaptive transcription factors and alleviating protein folding demand. One such transcription factor, X-box binding protein (XBP1)...

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Detalles Bibliográficos
Autores principales: Byrd, Andrew E., Brewer, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901129/
https://www.ncbi.nlm.nih.gov/pubmed/24710528
http://dx.doi.org/10.3390/cells1040738