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Intricately Regulated: A Cellular Toolbox for Fine-Tuning XBP1 Expression and Activity
Stress in the endoplasmic reticulum (ER) triggers the unfolded protein response (UPR), a signaling mechanism that allows cellular adaptation to ER stress by engaging pro-adaptive transcription factors and alleviating protein folding demand. One such transcription factor, X-box binding protein (XBP1)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901129/ https://www.ncbi.nlm.nih.gov/pubmed/24710528 http://dx.doi.org/10.3390/cells1040738 |