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Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet

The peroxisome proliferator-activated receptor-γ coactivators (PGC-1) are transcriptional coactivators with an important role in mitochondrial biogenesis and regulation of genes involved in the electron transport chain and oxidative phosphorylation in oxidative tissues including cardiac tissue. Thes...

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Detalles Bibliográficos
Autores principales: McCombie, Gregor, Medina-Gomez, Gema, Lelliott, Christopher J, Vidal-Puig, Antonio, Griffin, Julian L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901207/
https://www.ncbi.nlm.nih.gov/pubmed/24957515
http://dx.doi.org/10.3390/metabo2020366