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A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles

Cells produce electrophilic products with the potential to modify and affect the function of proteins. Chemoproteomic methods have provided a means to qualitatively inventory proteins targeted by endogenous electrophiles; however, ascertaining the potency and specificity of these reactions to identi...

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Detalles Bibliográficos
Autores principales: Wang, Chu, Weerapana, Eranthie, Blewett, Megan, Cravatt, Benjamin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901407/
https://www.ncbi.nlm.nih.gov/pubmed/24292485
http://dx.doi.org/10.1038/nmeth.2759