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ANGDelMut – a web-based tool for predicting and analyzing functional loss mechanisms of amyotrophic lateral sclerosis-associated angiogenin mutations

ANGDelMut is a web-based tool for predicting the functional consequences of missense mutations in the angiogenin (ANG) protein, which is associated with amyotrophic lateral sclerosis (ALS). Missense mutations in ANG result in loss of either ribonucleolytic activity or nuclear translocation activity...

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Detalles Bibliográficos
Autores principales: Padhi, Aditya K, Vasaikar, Suhas V, Jayaram, Bhyravabhotla, Gomes, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901456/
https://www.ncbi.nlm.nih.gov/pubmed/24555108
http://dx.doi.org/10.12688/f1000research.2-227.v3