The novel IGF-IR/Akt–dependent anticancer activities of glucosamine

BACKGROUND: Recent studies have shown that glucosamine inhibits the proliferation of various human cancer cell lines and downregulates the activity of COX-2, HIF-1α, p70S6K, and transglutaminase 2. Because the IGF-1R/Akt pathway is a common upstream regulator of p70S6K, HIF-1α, and COX-2, we hypothe...

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Detalles Bibliográficos
Autores principales: Song, Ki-Hoon, Kang, Ju-Hee, Woo, Jong-Kyu, Nam, Jeong-Seok, Min, Hye-Young, Lee, Ho-Young, Kim, Soo-Youl, Oh, Seung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901559/
https://www.ncbi.nlm.nih.gov/pubmed/24438088
http://dx.doi.org/10.1186/1471-2407-14-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901559/
https://www.ncbi.nlm.nih.gov/pubmed/24438088
http://dx.doi.org/10.1186/1471-2407-14-31

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