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Glutamine methylation in Histone H2A is an RNA Polymerase I dedicated modification

Nucleosomes are decorated with numerous post-translational modifications capable of influencing many DNA processes(1). Here, we describe a new class of histone modification, methylation of glutamine, occurring on yeast histone H2A at position 105 (Q105) and human H2A at Q104. We identify Nop1 as the...

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Detalles Bibliográficos
Autores principales: Tessarz, Peter, Santos-Rosa, Helena, Robson, Sam C., Sylvestersen, Kathrine B., Nelson, Christopher J, Nielsen, Michael L., Kouzarides, Tony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901671/
https://www.ncbi.nlm.nih.gov/pubmed/24352239
http://dx.doi.org/10.1038/nature12819