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Encoding Asymmetry of the N-Glycosylation Motif Facilitates Glycoprotein Evolution

Protein N-glycosylation is found in all domains of life and has a conserved role in glycoprotein folding and stability. In animals, glycoproteins transit through the Golgi where the N-glycans are trimmed and rebuilt with sequences that bind lectins, an innovation that greatly increases structural di...

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Detalles Bibliográficos
Autores principales: Williams, Ryan, Ma, Xiangyuan, Schott, Ryan K., Mohammad, Naveed, Ho, Chi Yip, Li, Carey F., Chang, Belinda S. W., Demetriou, Michael, Dennis, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901687/
https://www.ncbi.nlm.nih.gov/pubmed/24475074
http://dx.doi.org/10.1371/journal.pone.0086088