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Encoding Asymmetry of the N-Glycosylation Motif Facilitates Glycoprotein Evolution
Protein N-glycosylation is found in all domains of life and has a conserved role in glycoprotein folding and stability. In animals, glycoproteins transit through the Golgi where the N-glycans are trimmed and rebuilt with sequences that bind lectins, an innovation that greatly increases structural di...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901687/ https://www.ncbi.nlm.nih.gov/pubmed/24475074 http://dx.doi.org/10.1371/journal.pone.0086088 |