CSF1R inhibition delays cervical and mammary tumor growth in murine models by attenuating the turnover of tumor-associated macrophages and enhancing infiltration by CD8(+) T cells

Increased numbers of tumor-infiltrating macrophages correlate with poor disease outcome in patients affected by several types of cancer, including breast and prostate carcinomas. The colony stimulating factor 1 receptor (CSF1R) signaling pathway drives the recruitment of tumor-associated macrophages...

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Detalles Bibliográficos
Autores principales: Strachan, Debbie C, Ruffell, Brian, Oei, Yoko, Bissell, Mina J, Coussens, Lisa M, Pryer, Nancy, Daniel, Dylan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902121/
https://www.ncbi.nlm.nih.gov/pubmed/24498562
http://dx.doi.org/10.4161/onci.26968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902121/
https://www.ncbi.nlm.nih.gov/pubmed/24498562
http://dx.doi.org/10.4161/onci.26968

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