Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption

The CHRNA5-CHRNA3-CHRNB4 gene cluster, encoding the α5, α3, and β4 nicotinic acetylcholine receptor (nAChR) subunits, has been linked to nicotine dependence. The habenulo-interpeduncular (Hb-IPN) tract is particularly enriched in α3β4 nAChRs. We recently showed that modulation of these receptors in...

Descripción completa

Detalles Bibliográficos
Autores principales: Ślimak, Marta A., Ables, Jessica L., Frahm, Silke, Antolin-Fontes, Beatriz, Santos-Torres, Julio, Moretti, Milena, Gotti, Cecilia, Ibañez-Tallon, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902282/
https://www.ncbi.nlm.nih.gov/pubmed/24478678
http://dx.doi.org/10.3389/fnhum.2014.00012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902282/
https://www.ncbi.nlm.nih.gov/pubmed/24478678
http://dx.doi.org/10.3389/fnhum.2014.00012

Ejemplares similares