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Habenular expression of rare missense variants of the β4 nicotinic receptor subunit alters nicotine consumption

The CHRNA5-CHRNA3-CHRNB4 gene cluster, encoding the α5, α3, and β4 nicotinic acetylcholine receptor (nAChR) subunits, has been linked to nicotine dependence. The habenulo-interpeduncular (Hb-IPN) tract is particularly enriched in α3β4 nAChRs. We recently showed that modulation of these receptors in...

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Detalles Bibliográficos
Autores principales:	Ślimak, Marta A., Ables, Jessica L., Frahm, Silke, Antolin-Fontes, Beatriz, Santos-Torres, Julio, Moretti, Milena, Gotti, Cecilia, Ibañez-Tallon, Inés
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902282/ https://www.ncbi.nlm.nih.gov/pubmed/24478678 http://dx.doi.org/10.3389/fnhum.2014.00012

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