Gene expression analysis indicates CB1 receptor upregulation in the hippocampus and neurotoxic effects in the frontal cortex 3 weeks after single-dose MDMA administration in Dark Agouti rats

BACKGROUND: 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") is a widely used recreational drug known to impair cognitive functions on the long-run. Both hippocampal and frontal cortical regions have well established roles in behavior, memory formation and other cognitive tasks and dama...

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Detalles Bibliográficos
Autores principales: Petschner, Peter, Tamasi, Viola, Adori, Csaba, Kirilly, Eszter, Ando, Romeo D, Tothfalusi, Laszlo, Bagdy, Gyorgy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902429/
https://www.ncbi.nlm.nih.gov/pubmed/24378229
http://dx.doi.org/10.1186/1471-2164-14-930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902429/
https://www.ncbi.nlm.nih.gov/pubmed/24378229
http://dx.doi.org/10.1186/1471-2164-14-930

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