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PGBD5: a neural-specific intron-containing piggyBac transposase domesticated over 500 million years ago and conserved from cephalochordates to humans

BACKGROUND: piggyBac domain (PGBD) transposons are found in organisms ranging from fungi to humans. Three domesticated piggyBac elements have been described. In the ciliates Paramecium tetraurelia and Tetrahymena thermophila, homologs known as piggyMacs excise internal eliminated sequences from germ...

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Detalles Bibliográficos
Autores principales: Pavelitz, Thomas, Gray, Lucas T, Padilla, Stephanie L, Bailey, Arnold D, Weiner, Alan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902484/
https://www.ncbi.nlm.nih.gov/pubmed/24180413
http://dx.doi.org/10.1186/1759-8753-4-23