Utilizing Multiple in Silico Analyses to Identify Putative Causal SCN5A Variants in Brugada Syndrome

Brugada syndrome (BrS) is an inheritable sudden cardiac death disease mainly caused by SCN5A mutations. Traditional approaches can be costly and time-consuming if all candidate variants need to be validated through in vitro studies. Therefore, we developed a new approach by combining multiple in sil...

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Detalles Bibliográficos
Autores principales: Juang, Jyh-Ming Jimmy, Lu, Tzu-Pin, Lai, Liang-Chuan, Hsueh, Chia-Hsiang, Liu, Yen-Bin, Tsai, Chia-Ti, Lin, Lian-Yu, Yu, Chih-Chieh, Hwang, Juey-Jen, Chiang, Fu-Tien, Yeh, Sherri Shih-Fan, Chen, Wen-Pin, Chuang, Eric Y., Lai, Ling-Ping, Lin, Jiunn-Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902491/
https://www.ncbi.nlm.nih.gov/pubmed/24463578
http://dx.doi.org/10.1038/srep03850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902491/
https://www.ncbi.nlm.nih.gov/pubmed/24463578
http://dx.doi.org/10.1038/srep03850

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