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FK506 attenuates thymic output in patients with myasthenia gravis

INTRODUCTION: Myasthenia gravis (MG) is an antibody-mediated, T-cell-dependent autoimmune disease. The symptoms are caused by high-affinity IgG against the muscle acetylcholine receptor (AChR) at the neuromuscular junction. The production of these antibodies in B-cells depends on AChR-specific CD4(+...

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Detalles Bibliográficos
Autores principales: Mitsui, Takao, Kuroda, Yukiko, Ueno, Shu-ichi, Matsui, Naoko, Kaji, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902727/
https://www.ncbi.nlm.nih.gov/pubmed/24482655
http://dx.doi.org/10.5114/aoms.2013.39797