The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart

The Polycomb-group protein, Ezh2, is required for epigenetic gene silencing in the adult heart by unknown mechanism. We investigated the role of Ezh2 and non-coding RNAs in a mouse model of pressure overload using transverse aortic constriction (TAC) attenuated by the prototypical histone deacetylas...

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Detalles Bibliográficos
Autores principales: Mathiyalagan, Prabhu, Okabe, Jun, Chang, Lisa, Su, Yidan, Du, Xiao-Jun, El-Osta, Assam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902903/
https://www.ncbi.nlm.nih.gov/pubmed/24137001
http://dx.doi.org/10.1093/nar/gkt896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902903/
https://www.ncbi.nlm.nih.gov/pubmed/24137001
http://dx.doi.org/10.1093/nar/gkt896

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