Cargando…

The primary microRNA-208b interacts with Polycomb-group protein, Ezh2, to regulate gene expression in the heart

The Polycomb-group protein, Ezh2, is required for epigenetic gene silencing in the adult heart by unknown mechanism. We investigated the role of Ezh2 and non-coding RNAs in a mouse model of pressure overload using transverse aortic constriction (TAC) attenuated by the prototypical histone deacetylas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathiyalagan, Prabhu, Okabe, Jun, Chang, Lisa, Su, Yidan, Du, Xiao-Jun, El-Osta, Assam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902903/ https://www.ncbi.nlm.nih.gov/pubmed/24137001 http://dx.doi.org/10.1093/nar/gkt896

Ejemplares similares

Set7 mediated interactions regulate transcriptional networks in embryonic stem cells
por: Tuano, Natasha K., et al.
Publicado: (2016)

The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets
por: Van Dessel, Nele, et al.
Publicado: (2010)

Crol contributes to PRE-mediated repression and Polycomb group proteins recruitment in Drosophila
por: Erokhin, Maksim, et al.
Publicado: (2023)

SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression
por: Gjerstorff, Morten Frier, et al.
Publicado: (2014)

Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins
por: Pradeepa, Madapura M., et al.
Publicado: (2014)

Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin
por: Steffen, Philipp A., et al.
Publicado: (2013)

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes
por: Pasini, Diego, et al.
Publicado: (2010)

PRMT5-mediated histone arginine methylation antagonizes transcriptional repression by polycomb complex PRC2
por: Liu, Fan, et al.
Publicado: (2020)

Interdependence of PRC1 and PRC2 for recruitment to Polycomb Response Elements
por: Kahn, Tatyana G., et al.
Publicado: (2016)

The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis
por: Yuan, Liangbing, et al.
Publicado: (2020)

YY1 DNA binding and interaction with YAF2 is essential for Polycomb recruitment
por: Basu, Arindam, et al.
Publicado: (2014)

DNA elements tether canonical Polycomb Repressive Complex 1 to human genes
por: Barrasa, Juan I, et al.
Publicado: (2023)

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression
por: Wan, Junhu, et al.
Publicado: (2015)

BIM promoter directly targeted by EBNA3C in polycomb-mediated repression by EBV
por: Paschos, Kostas, et al.
Publicado: (2012)

Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin
por: Sakashita, Akihiko, et al.
Publicado: (2023)

Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene
por: Laursen, Kristian B., et al.
Publicado: (2013)

Arabidopsis DNA polymerase ϵ recruits components of Polycomb repressor complex to mediate epigenetic gene silencing
por: del Olmo, Iván, et al.
Publicado: (2016)

Atypical transcription of microRNA gene fragments
por: Song Gao, Jin, et al.
Publicado: (2010)

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation
por: Wang, Jun, et al.
Publicado: (2022)

PDGF induced microRNA alterations in cancer cells
por: Shao, Minghai, et al.
Publicado: (2011)

Highly efficient silencing of microRNA by heteroduplex oligonucleotides
por: Yoshioka, Kotaro, et al.
Publicado: (2019)

Efficiency and precision of microRNA biogenesis modes in plants
por: Moro, Belén, et al.
Publicado: (2018)

Ezh2 promotes clock function and hematopoiesis independent of histone methyltransferase activity in zebrafish
por: Zhong, Yingbin, et al.
Publicado: (2018)

Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication
por: Peña-Diaz, Javier, et al.
Publicado: (2013)

Novel roles of an intragenic G-quadruplex in controlling microRNA expression and cardiac function
por: Zhu, Min, et al.
Publicado: (2021)

NIPP1 maintains EZH2 phosphorylation and promoter occupancy at proliferation-related target genes
por: Minnebo, Nikki, et al.
Publicado: (2013)

Regulation of the positive transcriptional effect of PLZF through a non-canonical EZH2 activity
por: Koubi, Myriam, et al.
Publicado: (2018)

Revisiting the organization of Polycomb-repressed domains: 3D chromatin models from Hi-C compared with super-resolution imaging
por: Liu, Lei, et al.
Publicado: (2020)

Loss of EZH2 results in precocious mammary gland development and activation of STAT5-dependent genes
por: Yoo, Kyung Hyun, et al.
Publicado: (2015)

The Polycomb protein RING1B enables estrogen-mediated gene expression by promoting enhancer–promoter interaction and R-loop formation
por: Zhang, Yusheng, et al.
Publicado: (2021)

Cis-regulation of microRNA expression by scaffold/matrix-attachment regions
por: Chavali, Pavithra Lakshminarasimhan, et al.
Publicado: (2011)

A conserved BAH module within mammalian BAHD1 connects H3K27me3 to Polycomb gene silencing
por: Fan, Huitao, et al.
Publicado: (2021)

An intronic microRNA silences genes that are functionally antagonistic to its host gene
por: Barik, Sailen
Publicado: (2008)

Analysis of regulatory network topology reveals functionally distinct classes of microRNAs
por: Yu, Xueping, et al.
Publicado: (2008)

Tissue-specific regulation of mouse MicroRNA genes in endoderm-derived tissues
por: Gao, Yan, et al.
Publicado: (2011)

Estradiol-regulated microRNAs control estradiol response in breast cancer cells
por: Bhat-Nakshatri, Poornima, et al.
Publicado: (2009)

Identification of new microRNA-regulated genes by conserved targeting in plant species
por: Chorostecki, Uciel, et al.
Publicado: (2012)

EZH2 is required for mouse oocyte meiotic maturation by interacting with and stabilizing spindle assembly checkpoint protein BubRI
por: Qu, Yi, et al.
Publicado: (2016)

A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing
por: Flamand, Mathieu N., et al.
Publicado: (2017)

Validation of human microRNA target pathways enables evaluation of target prediction tools
por: Kern, Fabian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_51e8nmmem7ed6ohrqo4ku3o6ha