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Fast fitting to low resolution density maps: elucidating large-scale motions of the ribosome
Determining the conformational rearrangements of large macromolecules is challenging experimentally and computationally. Case in point is the ribosome; it has been observed by high-resolution crystallography in several states, but many others are known only from low-resolution methods including cryo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902909/ https://www.ncbi.nlm.nih.gov/pubmed/24081579 http://dx.doi.org/10.1093/nar/gkt906 |