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The ADAR RNA editing enzyme controls neuronal excitability in Drosophila melanogaster

RNA editing by deamination of specific adenosine bases to inosines during pre-mRNA processing generates edited isoforms of proteins. Recoding RNA editing is more widespread in Drosophila than in vertebrates. Editing levels rise strongly at metamorphosis, and Adar(5G1) null mutant flies lack editing...

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Detalles Bibliográficos
Autores principales: Li, Xianghua, Overton, Ian M., Baines, Richard A., Keegan, Liam P., O’Connell, Mary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902911/
https://www.ncbi.nlm.nih.gov/pubmed/24137011
http://dx.doi.org/10.1093/nar/gkt909