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High-resolution characterization of CPD hotspot formation in human fibroblasts

Repair of DNA lesions must occur within the chromatin landscape and is associated with alterations in histone modifications and nucleosome rearrangement. To directly associate these chromatin features with DNA damage and repair, it is necessary to be able to map DNA adducts. We have developed a cycl...

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Detalles Bibliográficos
Autores principales: Zavala, Anamaria G., Morris, Robert T., Wyrick, John J., Smerdon, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902913/
https://www.ncbi.nlm.nih.gov/pubmed/24137003
http://dx.doi.org/10.1093/nar/gkt912