Characterization of the interaction between HMGB1 and H3—a possible means of positioning HMGB1 in chromatin

High mobility group protein B1 (HMGB1) binds to the internucleosomal linker DNA in chromatin and abuts the nucleosome. Bending and untwisting of the linker DNA results in transmission of strain to the nucleosome core, disrupting histone/DNA contacts. An interaction between H3 and HMGB1 has been repo...

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Detalles Bibliográficos
Autores principales: Watson, Matthew, Stott, Katherine, Fischl, Harry, Cato, Laura, Thomas, Jean O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902940/
https://www.ncbi.nlm.nih.gov/pubmed/24157840
http://dx.doi.org/10.1093/nar/gkt950

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902940/
https://www.ncbi.nlm.nih.gov/pubmed/24157840
http://dx.doi.org/10.1093/nar/gkt950

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