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An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins

Determining the composition of messenger ribonucleoprotein (mRNP) particles is essential for a comprehensive understanding of the complex mechanisms underlying mRNA regulation, but is technically challenging. Here we present an RNA-based method to identify RNP components using a modified streptavidi...

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Detalles Bibliográficos
Autores principales: Leppek, Kathrin, Stoecklin, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902943/
https://www.ncbi.nlm.nih.gov/pubmed/24157833
http://dx.doi.org/10.1093/nar/gkt956