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A Phase 1 dose-ranging study examining the effects of a superabsorbent polymer (CLP) on fluid, sodium and potassium excretion in healthy subjects

BACKGROUND: CLP is an orally administered, non-absorbed, superabsorbent polymer being developed to increase fecal excretion of sodium, potassium and water in patients with heart failure and end-stage renal disease. This study was conducted to evaluate the safety of CLP, and to explore dose-related e...

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Detalles Bibliográficos
Autores principales: Henderson, Lee W, Dittrich, Howard C, Strickland, Alan, Blok, Thomas M, Newman, Richard, Oliphant, Thomas, Albrecht, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903027/
https://www.ncbi.nlm.nih.gov/pubmed/24460668
http://dx.doi.org/10.1186/2050-6511-15-2