Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations

BACKGROUND: Recent developments in high-throughput genomic technologies make it possible to have a comprehensive view of genomic alterations in tumors on a whole genome scale. Only a small number of somatic alterations detected in tumor genomes are driver alterations which drive tumorigenesis. Most...

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Detalles Bibliográficos
Autores principales: Youn, Ahrim, Simon, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903072/
https://www.ncbi.nlm.nih.gov/pubmed/24330428
http://dx.doi.org/10.1186/1471-2105-14-363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903072/
https://www.ncbi.nlm.nih.gov/pubmed/24330428
http://dx.doi.org/10.1186/1471-2105-14-363

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