Sequence Diversity in the pe_pgrs Genes of Mycobacterium tuberculosis Is Independent of Human T Cell Recognition

The Mycobacterium tuberculosis genome includes the large family of pe_pgrs genes, whose functions are unknown. Because of precedents in other pathogens in which gene families showing high sequence variation are involved in antigenic variation, a similar role has been proposed for the pe_pgrs genes....

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Detalles Bibliográficos
Autores principales: Copin, Richard, Coscollá, Mireia, Seiffert, Salome N., Bothamley, Graham, Sutherland, Jayne, Mbayo, Georgetta, Gagneux, Sebastien, Ernst, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903279/
https://www.ncbi.nlm.nih.gov/pubmed/24425732
http://dx.doi.org/10.1128/mBio.00960-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903279/
https://www.ncbi.nlm.nih.gov/pubmed/24425732
http://dx.doi.org/10.1128/mBio.00960-13

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