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Epigenetic Repression of Herpes Simplex Virus Infection by the Nucleosome Remodeler CHD3

Upon infection, the genome of herpes simplex virus is rapidly incorporated into nucleosomes displaying histone modifications characteristic of heterochromatic structures. The initiation of infection requires complex viral-cellular interactions that ultimately circumvent this repression by utilizing...

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Detalles Bibliográficos
Autores principales: Arbuckle, Jesse H., Kristie, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903285/
https://www.ncbi.nlm.nih.gov/pubmed/24425734
http://dx.doi.org/10.1128/mBio.01027-13