Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells

Abstract Zinc actions on synaptic transmission span the modulation of neurotransmitter receptors, transporters, activation of intracellular cascades and alterations in gene expression. Whether and how zinc affects inhibitory synaptic signalling in the dentate gyrus remains largely unexplored. We fou...

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Detalles Bibliográficos
Autores principales: Grauert, Antonia, Engel, Dominique, Ruiz, Arnaud J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Neuroscience: Cellular/Molecular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903352/
https://www.ncbi.nlm.nih.gov/pubmed/24081159
http://dx.doi.org/10.1113/jphysiol.2013.261420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903352/
https://www.ncbi.nlm.nih.gov/pubmed/24081159
http://dx.doi.org/10.1113/jphysiol.2013.261420

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