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Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA

Background. Marburg virus (MARV) infection causes severe morbidity and mortality in humans and nonhuman primates. Currently, there are no licensed therapeutics available for treating MARV infection. Here, we present the in vitro development and in vivo evaluation of lipid-encapsulated small interfer...

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Detalles Bibliográficos
Autores principales: Ursic-Bedoya, Raul, Mire, Chad E., Robbins, Marjorie, Geisbert, Joan B., Judge, Adam, MacLachlan, Ian, Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903369/
https://www.ncbi.nlm.nih.gov/pubmed/23990568
http://dx.doi.org/10.1093/infdis/jit465