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New Aspects of HERG K(+) Channel Function Depending upon Cardiac Spatial Heterogeneity

HERG K(+) channel, the genetic counterpart of rapid delayed rectifier K(+) current in cardiac cells, is responsible for many cases of inherited and drug-induced long QT syndromes. HERG has unusual biophysical properties distinct from those of other K(+) channels. While the conventional pulse protoco...

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Detalles Bibliográficos
Autores principales: Zhang, Pen, Guan, Ping, Bai, Xiao-Lu, Song, Zhi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903466/
https://www.ncbi.nlm.nih.gov/pubmed/24475014
http://dx.doi.org/10.1371/journal.pone.0072181